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Research Statement
AI generated · 1d agoAntonio Bertoletti's research centers on how T-cell immunity shapes viral control and liver damage, most extensively in hepatitis B. His senior-author work on the role of virus-specific CD8+ cells in liver damage and viral control during persistent HBV infection (794 citations) established a durable framework for understanding immune-mediated pathology, while later reviews on therapeutic strategies toward a cure for hepatitis B consolidated this into a translational agenda. During the COVID-19 pandemic he extended the same lens to SARS-CoV-2-specific T cell immunity in COVID-19 and SARS survivors and uninfected controls (1,888 citations), and showed that early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease. Earlier contributions include middle-author work on characterizing HBV-specific T-cell dysfunction in chronic infection (917 citations) and participation in a cross-tissue single-cell landscape of human monocytes and macrophages
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Sources
- Recognition
- Clarivate Highly Cited Researchers 2025 - Cross-Field. See the roster on JRNLClub.
- Publications & citations
- OpenAlex A5039286311 - works, citation counts, co-authors, and research topics.
- Affiliations & identity
- ORCID 0000-0002-2942-0485 - employment history, curated by the researcher.