David H. Haussler

David H. Haussler | JRNLClub

Research Statement

AI generated · 3d ago

David H. Haussler's most-cited work centers on the computational infrastructure that made vertebrate and cancer genomes navigable. His senior-authored UCSC Human Genome Browser underpins how researchers visualize and query reference assemblies, while the Xena platform for visualizing and interpreting cancer genomics data extends that same accessibility to tumor datasets. A parallel thread concerns evolutionary sequence analysis: his work identifying ultraconserved and evolutionarily conserved elements across vertebrate, insect, worm, and yeast genomes helped define how deeply conserved regulatory regions are detected. Beyond these, Haussler contributed as a middle author to large consortia, including the integrative analysis of 111 reference human epigenomes and GENCODE's reference human genome annotation for ENCODE, both of which relied on the annotation and comparative frameworks his group helped build. Collaborations with Benedict Paten and Brian J. Raney on vertebrate assembly and comparative genomics reflect this consortium-facing strand. No software, datasets, grants, or patents beyond publications are indexed. Taken together, the named works trace a consistent arc: from probabilistic sequence models toward shared, browsable resources that let the broader genomics community interpret genomes and tumors alike.

Most Cited Works

Towards complete and error-free genome assemblies of all vertebrate species

Arang Rhie, Shane A McCarthy, Olivier Fedrigo, Joana Damas, Giulio Formenti, Sergey Koren, Marcela Uliano-Silva, William Chow, Arkarachai Fungtammasan, Juwan Kim, Chul Lee, Byung June Ko, Mark Chaisson, Gregory L Gedman, Lindsey J Cantin, Francoise Thibaud-Nissen, Leanne Haggerty, Iliana Bista, Michelle Smith, Bettina Haase, Jacquelyn Mountcastle, Sylke Winkler, Sadye Paez, Jason Howard, Sonja C Vernes, Tanya M Lama, Frank Grutzner, Wesley C Warren, Christopher N Balakrishnan, Dave Burt, Julia M George, Matthew T Biegler, David Iorns,

Research Areas

Genomics and Phylogenetic StudiesCancer Genomics and DiagnosticsChromosomal and Genetic VariationsBioinformatics and Genomic NetworksGenomic variations and chromosomal abnor

Affiliations & Education

Education

1979–1982
University of Colorado Boulder(US)
PhD · Computer Science
1976–1979
California Polytechnic State University(US)
MS · Applied Mathematics
1971–1975
Connecticut College(US)
BA · Mathematics

Employment

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A draft human pangenome reference

Wen-Wei Liao, Mobin Asri, Jana Ebler, Daniel Doerr, Marina Haukness, Glenn Hickey, Shuangjia Lu, Julian K Lucas, Jean Monlong, Haley J Abel, Silvia Buonaiuto, Xian H Chang, Haoyu Cheng, Justin Chu, Vincenza Colonna, Jordan M Eizenga, Xiaowen Feng, Christian Fischer, Robert S Fulton, Shilpa Garg, Cristian Groza, Andrea Guarracino, William T Harvey, Simon Heumos, Kerstin Howe, Miten Jain, Tsung-Yu Lu, Charles Markello, Fergal J Martin, Matthew W Mitchell, Katherine M Munson, Moses Njagi Mwaniki, Adam M Novak, Hugh E Olsen, Trevor Pesout, David Porubsky, Pjotr Prins, Jonas A Sibbesen, Jouni Sirén, Chad Tomlinson, Flavia Villani, Mitchell R Vollger, Lucinda L Antonacci-Fulton, Gunjan Baid, Carl A Baker, Anastasiya Belyaeva, Konstantinos Billis, Andrew Carroll, Pi-Chuan Chang, Sarah Cody, Daniel E Cook, Robert M Cook-Deegan, Omar E Cornejo, Mark Diekhans, Peter Ebert, Susan Fairley, Olivier Fedrigo, Adam L Felsenfeld, Giulio Formenti, Adam Frankish, Yan Gao, Nanibaa' A Garrison, Carlos Garcia Giron, Richard E Green, Leanne Haggerty, Kendra Hoekzema, Thibaut Hourlier, Hanlee P Ji, Eimear E Kenny, Barbara A Koenig, Alexey Kolesnikov, Jan O Korbel, Jennifer Kordosky, Sergey Koren, HoJoon Lee, Alexandra P Lewis, Hugo Magalhães, Santiago Marco-Sola, Pierre Marijon, Ann McCartney, Jennifer McDaniel, Jacquelyn Mountcastle, Maria Nattestad, Sergey Nurk, Nathan D Olson, Alice B Popejoy, Daniela Puiu, Mikko Rautiainen, Allison A Regier, Arang Rhie, Samuel Sacco, Ashley D Sanders, Valerie A Schneider, Baergen I Schultz, Kishwar Shafin, Michael W Smith, Heidi J Sofia, Ahmad N Abou Tayoun, Françoise Thibaud-Nissen, Francesca Floriana Tricomi, Justin Wagner, Brian Walenz, Jonathan M D Wood, Aleksey V Zimin, Guillaume Bourque, Mark J P Chaisson, Paul Flicek, Adam M Phillippy, Justin M Zook, Evan E Eichler, David Haussler, Ting Wang, Erich D Jarvis, Karen H Miga, Erik Garrison, Tobias Marschall, Ira M Hall, Heng Li, Benedict Paten

Nature2023

1,252Citations

Dense sampling of bird diversity increases power of comparative genomics

Shaohong Feng, Josefin Stiller, Yuan Deng, Joel Armstrong, Qi Fang, Andrew Hart Reeve, Duo Xie, Guangji Chen, Chunxue Guo, Brant C Faircloth, Bent Petersen, Zongji Wang, Qi Zhou, Mark Diekhans, Wanjun Chen, Sergio Andreu-Sánchez, Ashot Margaryan, Jason Travis Howard, Carole Parent, George Pacheco, Mikkel-Holger S Sinding, Lara Puetz, Emily Cavill, Ângela M Ribeiro, Leopold Eckhart, Jon Fjeldså, Peter A Hosner, Robb T Brumfield, Les Christidis, Mads F Bertelsen, Thomas Sicheritz-Ponten, Dieter Thomas Tietze, Bruce C Robertson, Gang Song, Gerald Borgia, Santiago Claramunt, Irby J Lovette, Saul J Cowen, Peter Njoroge, John Philip Dumbacher, Oliver A Ryder, Jérôme Fuchs, Michael Bunce, David W Burt, Joel Cracraft, Guanliang Meng, Shannon J Hackett, Peter G Ryan, Knud Andreas Jønsson, Ian G Jamieson, Rute R da Fonseca, Edward L Braun, Peter Houde, Siavash Mirarab, Alexander Suh, Bengt Hansson, Suvi Ponnikas, Hanna Sigeman, Martin Stervander, Paul B Frandsen, Henriette van der Zwan, Rencia van der Sluis, Carina Visser, Christopher N Balakrishnan, Andrew G Clark, John W Fitzpatrick, Reed Bowman, Nancy Chen, Alison Cloutier, Timothy B Sackton, Scott V Edwards, Dustin J Foote, Subir B Shakya, Frederick H Sheldon, Alain Vignal, André E R Soares, Beth Shapiro, Jacob González-Solís, Joan Ferrer-Obiol, Julio Rozas, Marta Riutort, Anna Tigano, Vicki Friesen, Love Dalén, Araxi O Urrutia, Tamás Székely, Yang Liu, Michael G Campana, André Corvelo, Robert C Fleischer, Kim M Rutherford, Neil J Gemmell, Nicolas Dussex, Henrik Mouritsen, Nadine Thiele, Kira Delmore, Miriam Liedvogel, Andre Franke, Marc P Hoeppner, Oliver Krone, Adam M Fudickar, Borja Milá, Ellen D Ketterson, Andrew Eric Fidler, Guillermo Friis, Ángela M Parody-Merino, Phil F Battley, Murray P Cox, Nicholas Costa Barroso Lima, Francisco Prosdocimi, Thomas Lee Parchman, Barney A Schlinger, Bette A Loiselle, John G Blake, Haw Chuan Lim, Lainy B Day, Matthew J Fuxjager, Maude W Baldwin, Michael J Braun, Morgan Wirthlin, Rebecca B Dikow, T Brandt Ryder, Glauco Camenisch, Lukas F Keller, Jeffrey M DaCosta, Mark E Hauber, Matthew I M Louder, Christopher C Witt, Jimmy A McGuire, Joann Mudge, Libby C Megna, Matthew D Carling, Biao Wang, Scott A Taylor, Glaucia Del-Rio, Alexandre Aleixo, Ana Tereza Ribeiro Vasconcelos, Claudio V Mello, Jason T Weir, David Haussler, Qiye Li, Huanming Yang, Jian Wang, Fumin Lei, Carsten Rahbek, M Thomas P Gilbert, Gary R Graves, Erich D Jarvis, Benedict Paten, Guojie Zhang

Nature2020

469Citations