Erik Jacques's indexed work centers on regenerative medicine, particularly its impact on therapy translation as explored in a highly cited 2020 publication. Their research frequently employs advanced biomimetic systems, including a mini-IDLE 3D biomimetic culture assay to investigate muscle stem cell quiescence and niche repopulation. Jacques also investigates therapeutic materials, such as collagen-based microcapsules for stem cell therapies in infarcted myocardium, and contributes to the understanding of aging biomarkers, with a forthcoming work on invigorating discovery and clinical translation of aging biomarkers. Publicly indexed outputs suggest a focus on developing and utilizing sophisticated models for studying muscle physiology and disease. For instance, Jacques contributed to a study on de novo revertant fiber formation and therapy testing in a 3D culture model of Duchenne muscular dystrophy skeletal muscle